Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.44 |
| ▸ | KLK1 | P06870 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857101 | 0.97 | MMP9 (0.45) | MMP2MMP9MMP8KLKB1KLK1 | |
| SCHEMBL8162601 | 0.87 | MMP2 (0.50) | MMP2MMP9MMP8FCER2 | |
| SCHEMBL7860837 | 0.82 | MMP8 (0.44) | MMP2MMP9MMP8FCER2 | |
| SCHEMBL7857944 | 0.82 | MMP9 (0.45) | MMP2MMP9MMP8FCER2 | |
| Trifluoroacetic Acid SCHEMBL7857833 | 0.82 | MMP2 (0.46) | MMP2MMP9MMP8MCHR1FCER2 | |
| SCHEMBL7860797 | 0.81 | MMP9 (0.46) | MMP2MMP9MMP8FCER2 | |
| SCHEMBL7857825 | 0.81 | CALCRL (0.46) | MMP2MMP9MMP8 | |
| SCHEMBL7857865 | 0.78 | FCER2 (0.60) | MMP2MMP9MMP8KLKB1FCER2 | |
| SCHEMBL7857107 | 0.77 | MMP9 (0.46) | MMP2MMP9MMP8FCER2 | |
| SCHEMBL7857847 | 0.76 | MMP2 (0.47) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |