Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7857833 | 0.94 | MMP2 (0.46) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7857911 | 0.87 | MMP2 (0.44) | MMP2MMP9MMP8FCER2 | |
| SCHEMBL7857101 | 0.84 | MMP9 (0.45) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7857944 | 0.84 | MMP9 (0.45) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7860797 | 0.84 | MMP9 (0.46) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7857825 | 0.83 | CALCRL (0.46) | MMP2MMP9MMP8 | |
| SCHEMBL7860837 | 0.82 | MMP8 (0.44) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7857107 | 0.79 | MMP9 (0.46) | MMP2MMP9MMP8MMP1FCER2 | |
| SCHEMBL7857847 | 0.78 | MMP2 (0.47) | MMP2OPRK1TPH1 | |
| SCHEMBL1244207 | 0.77 | SCN9A (0.51) | MMP2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |