Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858657 | 0.81 | TAS1R3 (0.38) | TP53TDP1ALDH1A1SMN1; SMN2TRPA1 | |
| SCHEMBL1053845 | 0.76 | ELANE (0.43) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL706768 | 0.73 | HIF1A (0.38) | ACHEKDM4EALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL14732558 | 0.72 | ALDH1A1 (0.40) | TP53TDP1PTGS2KDM4EALDH1A1 | |
| SCHEMBL7864084 | 0.70 | ELANE (0.33) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Styrene SCHEMBL27879903 | 0.69 | ALDH1A1 (0.47) | TDP1PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24616666 | 0.69 | TP53 (0.50) | TP53TDP1PTGS2ALDH1A1TRPA1 | |
| SCHEMBL9720583 | 0.68 | TDP1 (0.46) | TP53TDP1PTGS2ACHEKDM4E | |
| Styrene SCHEMBL28022925 | 0.68 | ALDH1A1 (0.50) | MCL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10613889 | 0.68 | TP53 (0.54) | TP53TDP1PTGS2ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |