SCHEMBL786091

SCHEMBL786091

C=C(c1ccc(O)cc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
HSD17B10 Q99714 3/20 0.43
HTT P42858 2/20 0.43
GFER P55789 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
ESR1 P03372 5/20 0.39
ESR2 Q92731 3/20 0.39
LMNA P02545 4/20 0.33
PKM P14618 2/20 0.33
HPGD P15428 2/20 0.33
KIF11 P52732 1/20 0.33
ALDH5A1 P51649 1/20 0.32
ABAT P80404 1/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
NPC1 O15118 2/20 0.32
NFKB1 P19838 2/20 0.32
RAB9A P51151 2/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786215 0.98 MAPT (0.41) MAPTHSD17B10HTTGFERGPR55
SCHEMBL1697058 0.98 MAPT (0.41) MAPTHSD17B10HTTGFERGPR55
SCHEMBL685624 0.76 MAPT (0.52) MAPTHSD17B10HTTGFERGPR55
SCHEMBL28729268 0.73 ESR1 (0.36) MAPTHSD17B10HTTGFERGPR55
Perflutren SCHEMBL8603202 0.72 ESR1 (0.57) MAPTHSD17B10ESR1ESR2LMNA
SCHEMBL27056090 0.67 HSD17B10 (0.52) MAPTHSD17B10HTTGFERGPR55
SCHEMBL20482416 0.67 CES2 (0.39) HTTLMNACA1CA2CA5A
SCHEMBL3679251 0.66 ESR1 (0.56) MAPTHSD17B10ESR1ESR2LMNA
SCHEMBL1353159 0.66 ESR1 (0.56) MAPTHSD17B10ESR1ESR2LMNA
SCHEMBL542378 0.66 ESR1 (0.44) MAPTHSD17B10HTTGFERGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726976-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9726976-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9405187-B2 Salt, acid generator and resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-02 US disclosed
US-9346750-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-24 US disclosed
US-9346750-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-24 US disclosed
US-9229320-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-05 US disclosed
US-9063414-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-23 US disclosed
US-9063414-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-23 US disclosed
US-8993210-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-31 US disclosed
US-8993210-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-31 US disclosed
US-20110117494-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
US-20110117495-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
US-20110111342-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-05-12 US disclosed
US-20110091808-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110091807-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110076617-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 US disclosed
US-20110065040-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed
US-20110065047-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICHAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed
US-20110065041-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed
US-20110059400-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091808-A1 PHOTORESIST COMPOSITION ASIC1, ASIC3, SUN2 MAPT 54/4885HSD17B10 3788/4885HTT 740/4885
US-20110059400-A1 PHOTORESIST COMPOSITION C1R, C1S, CCNT1 MAPT 708/4885HSD17B10 3383/4885HTT 801/4885
US-20110065047-A1 PHOTORESIST COMPOSITION C1R, C1S, RER1 MAPT 1598/4885HSD17B10 1413/4885HTT 520/4885
US-20110117495-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME C1S, H1-0, C1R MAPT 1882/4885HSD17B10 1166/4885HTT 1400/4885
US-20110065040-A1 PHOTORESIST COMPOSITION C1R, P4HA1, C1S MAPT 1824/4885HSD17B10 855/4885HTT 537/4885
US-20110117494-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME C1S, C1R, AFF1 MAPT 2230/4885HSD17B10 1756/4885HTT 1693/4885
US-20110091807-A1 PHOTORESIST COMPOSITION H1-0, H1-2, H1-3 MAPT 923/4885HSD17B10 2630/4885HTT 988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.