SCHEMBL685624

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19385678	0.80	PLOD2 (0.45)	CA1CA2NPC1RAB9APTGS1
	SCHEMBL4263908	0.78	MASP2 (0.41)	MAPTHSD17B10ESR1ESR2LMNA
	SCHEMBL928167	0.78	CES2 (0.54)	MEN1KMT2AHPGDALDH1A1KIF11
	SCHEMBL15202933	0.78	CA2 (0.45)	HTTLMNAMEN1KMT2ACA2
	SCHEMBL16650	0.78	CES2 (0.42)	MAPTHTTLMNACA1CA2
	SCHEMBL20973221	0.78	CES2 (0.42)	LMNACA1CA2CYP3A4ALOX15
	SCHEMBL32009	0.77	CES1 (0.52)	MAPTHSD17B10LMNAMEN1KMT2A
	SCHEMBL9414658	0.76	TSHR (0.55)	HSD17B10CA1CA2ALOX15HPGD
	SCHEMBL786091	0.76	MAPT (0.43)	MAPTHSD17B10HTTGFERGPR55
	SCHEMBL27056090	0.75	HSD17B10 (0.52)	MAPTHSD17B10HTTGFERGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.