Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863285 | 0.86 | ITGB3 (0.48) | F10F2MAPTMAPK1POLB | |
| SCHEMBL7864169 | 0.86 | F10 (0.48) | F10F2MAPTMAPK1POLB | |
| SCHEMBL8501220 | 0.75 | ITGB3 (0.42) | POLBMEN1KMT2AITGB3ITGA2B | |
| Nitrous Acid SCHEMBL5997813 | 0.74 | F10 (0.44) | F10MAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL7863273 | 0.74 | FFAR1 (0.43) | MAPTMAPK1POLBLMNAITGB3 | |
| SCHEMBL7856520 | 0.74 | F10 (0.51) | F10F2MAPTMAPK1POLB | |
| SCHEMBL7863151 | 0.74 | KMT2A (0.57) | F10MEN1KMT2A | |
| SCHEMBL7178642 | 0.74 | ALDH1A1 (0.55) | F10F2MAPTPOLBALDH1A1 | |
| SCHEMBL8431172 | 0.73 | MAPT (0.46) | F2MAPTMAPK1POLBPRSS1 | |
| SCHEMBL7861966 | 0.73 | NAMPT (0.55) | MAPTMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |