Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870547 | 0.92 | HTT (0.48) | ALDH1A1HSD17B10HTTKMT2AGAA | |
| SCHEMBL7862846 | 0.91 | LMNA (0.47) | ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7869173 | 0.89 | RAB9A (0.44) | ALDH1A1HTTKMT2ASMN1; SMN2HPGD | |
| SCHEMBL9018263 | 0.88 | HTT (0.51) | ALDH1A1HSD17B10HTTKMT2AGAA | |
| SCHEMBL8868092 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HTTKMT2AGAA | |
| SCHEMBL7871660 | 0.86 | SMN1; SMN2 (0.42) | HTTKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7862689 | 0.85 | RAB9A (0.43) | ALDH1A1HTTKMT2ASMN1; SMN2HPGD | |
| SCHEMBL7862681 | 0.85 | HSD17B10 (0.43) | HSD17B10HTTKMT2ASMN1; SMN2HPGD | |
| SCHEMBL9018178 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HTTKMT2AGAA | |
| SCHEMBL7862723 | 0.84 | SMN1; SMN2 (0.44) | HTTKMT2AGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |