Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862847 | 0.92 | ALDH1A1 (0.47) | HTTHSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL7867896 | 0.90 | LMNA (0.49) | HTTALDH1A1GAAKMT2A | |
| SCHEMBL8869693 | 0.87 | HSD17B10 (0.50) | HTTHSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL9018263 | 0.86 | HTT (0.51) | HTTHSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL7874547 | 0.85 | SMN1; SMN2 (0.43) | HTTHSD17B10KMT2A | |
| SCHEMBL7862681 | 0.83 | HSD17B10 (0.43) | HTTHSD17B10KMT2A | |
| SCHEMBL9018178 | 0.83 | ALDH1A1 (0.49) | HTTHSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL9018476 | 0.83 | HTT (0.50) | HTTHSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL7867890 | 0.83 | POLB (0.40) | ALDH1A1GAAKMT2A | |
| SCHEMBL7871628 | 0.83 | HTT (0.53) | HTTHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |