Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864274 | 0.88 | LMNA (0.43) | ITGB3MAPTLMNAHTT | |
| SCHEMBL7864633 | 0.86 | MAPT (0.41) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL7856467 | 0.85 | MEN1 (0.42) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL7863288 | 0.79 | SIRT2 (0.48) | KMT2AITGB3MAPTLMNARAB9A | |
| SCHEMBL7864322 | 0.76 | AURKA (0.41) | GAAITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL6779576 | 0.73 | RHOC (0.48) | CYP1A2GAATACR1BCHELMNA | |
| SCHEMBL7856464 | 0.72 | TP53 (0.49) | MEN1KMT2AGAAITGB3BCHE | |
| Hydrochloric Acid SCHEMBL6775633 | 0.72 | RHOC (0.47) | CYP1A2GAATACR1BCHELMNA | |
| SCHEMBL8500652 | 0.72 | FFAR1 (0.38) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL7864673 | 0.71 | MAPT (0.42) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |