Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 3/20 | 0.31 |
| ▸ | ESRRA | P11474 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865744 | 0.84 | CES2 (0.43) | MAPTCYP1A1CYP1B1CES2KDM4E | |
| SCHEMBL7871959 | 0.76 | MAOB (0.32) | MAPTCES2LMNA | |
| SCHEMBL6814288 | 0.74 | CES2 (0.53) | MAPTCES2KDM4EALDH1A1HPGD | |
| SCHEMBL6814286 | 0.74 | CES2 (0.53) | MAPTCES2KDM4EALDH1A1HPGD | |
| SCHEMBL6815355 | 0.72 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL6815360 | 0.72 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL7866858 | 0.70 | DDR1 (0.34) | POLBMAPT | |
| SCHEMBL31019712 | 0.69 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL7575928 | 0.69 | VNN1 (0.37) | POLBMAPTKDM4E | |
| SCHEMBL7846221 | 0.66 | KMT2A (0.43) | POLBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |