Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783828 | 0.89 | MEN1 (0.41) | EPHX2MAOBMAOAMAPTALDH1A1 | |
| SCHEMBL7569653 | 0.80 | IDO1 (0.50) | EPHX2MAOBMAOAIDO1ALDH1A1 | |
| SCHEMBL7575928 | 0.75 | VNN1 (0.37) | MAPTKMT2APOLBGAA | |
| SCHEMBL6815139 | 0.73 | CA2 (0.51) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7785594 | 0.71 | L3MBTL1 (0.46) | MAOBIDO1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7868541 | 0.68 | NPSR1 (0.36) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7571037 | 0.68 | HIF1A (0.35) | IDO1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7861383 | 0.67 | HIF1A (0.39) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7784388 | 0.65 | NPFFR2 (0.37) | IDO1NPC1KMT2APOLBGAA | |
| SCHEMBL7846221 | 0.64 | KMT2A (0.43) | MAOBKMT2APOLBGRIN2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |