Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574752 | 0.92 | L3MBTL1 (0.53) | MEN1KMT2ALMNABCL2BCL2L1 | |
| SCHEMBL7870480 | 0.91 | SCN3A (0.46) | MEN1KMT2ASCN3ALMNABCL2 | |
| SCHEMBL7862672 | 0.91 | L3MBTL1 (0.47) | MEN1KMT2ALMNABCL2BCL2L1 | |
| SCHEMBL9574869 | 0.90 | CA1 (0.47) | MEN1KMT2ABCL2L1MCL1NPC1 | |
| SCHEMBL7862839 | 0.90 | SMN1; SMN2 (0.48) | LMNAPKMNAMPTPPARAKDM4E | |
| SCHEMBL9574735 | 0.89 | ALDH1A1 (0.52) | MEN1KMT2ALMNAPKM | |
| SCHEMBL7869445 | 0.89 | PKM (0.43) | MEN1KMT2APKMNAMPTKDM4E | |
| SCHEMBL9018559 | 0.88 | MEN1 (0.53) | MEN1KMT2ASCN3ALMNANPC1 | |
| SCHEMBL7871609 | 0.87 | P4HTM (0.55) | BCL2L1MCL1NAMPTP4HTM | |
| SCHEMBL8868481 | 0.87 | HDAC3 (0.51) | MEN1KMT2ASCN3ALMNABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |