SCHEMBL7870355

SCHEMBL7870355

CCON=C(C(C)=NO)c1ccc(OC(C)c2ccc(Cl)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
LTB4R Q15722 6/20 0.38
LTB4R2 Q9NPC1 6/20 0.38
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 1/20 0.33
SIGMAR1 Q99720 2/20 0.33
USP2 O75604 1/20 0.33
PTGS2 P35354 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RAB9A P51151 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871754 0.79 POLB (0.43) POLBLTB4RLTB4R2MEN1KMT2A
SCHEMBL7871757 0.79 POLB (0.43) POLBLTB4RLTB4R2MEN1KMT2A
SCHEMBL7863545 0.74 HIF1A (0.49) LTB4RLTB4R2PTGS2
SCHEMBL7863470 0.74 LTB4R (0.40) LTB4RLTB4R2MEN1KMT2AL3MBTL1
SCHEMBL8030802 0.73 HIF1A (0.40) LTB4RLTB4R2PTGS2
SCHEMBL8723236 0.72 HTT (0.41) KMT2AL3MBTL1SMN1; SMN2RAB9AALDH1A1
SCHEMBL7868865 0.71 L3MBTL1 (0.47) POLBLTB4RLTB4R2MEN1KMT2A
SCHEMBL6839015 0.71 MMP1 (0.33) POLBL3MBTL1GAASMN1; SMN2RAB9A
SCHEMBL823263 0.70 HPGD (0.59) POLBLTB4RLTB4R2MEN1KMT2A
SCHEMBL8501552 0.70 TRPA1 (0.43) POLBMEN1KMT2AL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313344-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed
EP-0984923-A1 O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES Novartis AG (CH) 2000-03-15 EP disclosed
WO-1998054125-A1 O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES NOVARTIS AG (CH) 1998-12-03 WO disclosed