Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182634 | 0.74 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6182630 | 0.74 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6986107 | 0.72 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7059883 | 0.71 | FAAH (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4563760 | 0.70 | HIF1A (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7121391 | 0.70 | FAAH (0.41) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27789463 | 0.69 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL10508162 | 0.69 | ALDH1A1 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7062987 | 0.69 | FAAH (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6981975 | 0.68 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316490-B1 | FOR THERAPY OF PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, DEMENTIA, CONTROLLING PAIN | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |