Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873175 | 0.80 | LTA4H (0.64) | KMT2ALTA4HHPGDTSHRCYP2D6 | |
| SCHEMBL3541038 | 0.80 | LMNA (0.65) | KMT2AHPGDTSHRHSD17B10LMNA | |
| SCHEMBL646758 | 0.78 | RAB9A (0.46) | KMT2ALTA4HHPGDTSHRHSD17B10 | |
| SCHEMBL9079405 | 0.71 | AOC3 (0.47) | KMT2AHPGDTSHRHSD17B10LMNA | |
| SCHEMBL7019937 | 0.70 | NPC1 (0.56) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL23828926 | 0.69 | LTA4H (0.55) | KMT2ALTA4HHPGDTSHRHSD17B10 | |
| SCHEMBL5091164 | 0.67 | POLB (0.43) | HPGDTSHRRAB9AL3MBTL1 | |
| SCHEMBL21959073 | 0.66 | ALDH1A1 (0.43) | KMT2AHPGDTSHRLMNARAB9A | |
| SCHEMBL13232422 | 0.66 | L3MBTL1 (0.59) | KMT2AHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL23828911 | 0.66 | LTA4H (0.58) | KMT2ALTA4HHPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2007-H1 | INSECTICIDES | FMC CORPORATION | 2001-12-04 | — | — | US | disclosed |
| WO-1997026252-A1 | INSECTICIDAL N-HETEROCYCLYLALKYL- OR N-[(POLYCYCLYL)-ALKYL]-N'-SUBSTITUTED PIPERAZINES | FMC CORPORATION (US) | 1997-07-24 | — | — | WO | disclosed |