Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301415 | 0.73 | MEN1 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16291450 | 0.70 | MEN1 (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9645416 | 0.68 | MEN1 (0.40) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL9645259 | 0.68 | NPC1 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9645295 | 0.68 | GSK3A (0.40) | ALDH1A1POLBGAAL3MBTL1MGLL | |
| SCHEMBL9645868 | 0.63 | APP (0.40) | ALDH1A1TSHRPKM | |
| SCHEMBL28820783 | 0.62 | MEN1 (0.33) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9645288 | 0.62 | GAA (0.44) | ALDH1A1GAASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL22357884 | 0.61 | KMT2A (0.48) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8526316 | 0.59 | MGLL (0.59) | ALDH1A1MEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231744-B1 | SUBSTITUTED PYRROL-1-YLPHENYLDIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0167995-B1 | (PYRROL-1-YL)-PHENYL-DIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1989-01-04 | — | — | EP | claimed |
| US-4710496-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS, GASTRIC ACID INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-01 | — | — | US | claimed |
| EP-0231744-A1 | Substituted pyrrol-1-ylphenyldihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1987-08-12 | — | — | EP | claimed |
| EP-0167995-A2 | (Pyrrol-1-yl)-phenyl-dihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | claimed |
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-0231744-B1 | SUBSTITUTED PYRROL-1-YLPHENYLDIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0231744-B1 | SUBSTITUTED PYRROL-1-YLPHENYLDIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0167995-B1 | (PYRROL-1-YL)-PHENYL-DIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0167995-B1 | (PYRROL-1-YL)-PHENYL-DIHYDROPYRIDAZINONES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1989-01-04 | — | — | EP | disclosed |
| US-4710496-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS, GASTRIC ACID INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-01 | — | — | US | disclosed |
| US-4710496-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS, GASTRIC ACID INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-01 | — | — | US | disclosed |
| US-4710496-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS, GASTRIC ACID INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-01 | — | — | US | disclosed |
| EP-0231744-A1 | Substituted pyrrol-1-ylphenyldihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1987-08-12 | — | — | EP | disclosed |
| EP-0231744-A1 | Substituted pyrrol-1-ylphenyldihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1987-08-12 | — | — | EP | disclosed |
| EP-0231744-A1 | Substituted pyrrol-1-ylphenyldihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1987-08-12 | — | — | EP | disclosed |
| EP-0167995-A2 | (Pyrrol-1-yl)-phenyl-dihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0167995-A2 | (Pyrrol-1-yl)-phenyl-dihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0167995-A2 | (Pyrrol-1-yl)-phenyl-dihydropyridazinones, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | disclosed |