Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867676 | 0.91 | EPHX2 (0.42) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL7870444 | 0.86 | P4HTM (0.46) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL8867785 | 0.86 | ALKBH2 (0.52) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL7867824 | 0.80 | P4HTM (0.44) | ALDH1A1EPHX2SCN9ASCN10ARAB9A | |
| SCHEMBL9574732 | 0.78 | SMN1; SMN2 (0.45) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL7862823 | 0.78 | MCL1 (0.48) | BCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL8868286 | 0.78 | P4HTM (0.55) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL8869733 | 0.78 | FTO (0.53) | MEN1ALDH1A1HPGDKMT2AALKBH2 | |
| SCHEMBL8869527 | 0.78 | ALKBH2 (0.54) | MEN1ALDH1A1HPGDKMT2AEPHX2 | |
| SCHEMBL7869468 | 0.77 | EPHX2 (0.44) | MEN1ALDH1A1HPGDKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |