Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167589 | 0.82 | — | — | |
| Alanine SCHEMBL3261340 | 0.78 | ADRA2B (0.40) | ADRA2BADRA2CNISCHADRA2AHTR1A | |
| SCHEMBL9740242 | 0.73 | ALDH1A1 (0.51) | ALDH1A1ADRA2BADRA2CNISCHADRA2A | |
| SCHEMBL7133362 | 0.71 | — | — | |
| SCHEMBL9815902 | 0.70 | RAD52 (0.41) | ADRA2BADRA2CNISCHADRA2AHTR1A | |
| Hydrochloric Acid SCHEMBL11625324 | 0.68 | NISCH (0.47) | ALDH1A1ADRA2BADRA2CNISCHADRA2A | |
| SCHEMBL4702212 | 0.66 | NISCH (0.42) | ALDH1A1ADRA2BADRA2CNISCHADRA2A | |
| Octanedioate SCHEMBL4052467 | 0.63 | TSHR (0.71) | ABCC4MAPTALDH1A1LMNATSHR | |
| Azelaic Acid SCHEMBL4051535 | 0.63 | TSHR (0.71) | ABCC4MAPTALDH1A1LMNATSHR | |
| Sebacic Acid SCHEMBL4053732 | 0.63 | TSHR (0.71) | ABCC4MAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006316-B2 | Organometallic compositions and coating compositions | KING INDUSTRIES, INC. (US) | 2015-04-14 | — | — | US | claimed |
| US-20120070569-A1 | ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS | KING INDUSTRIES, INC. (US) | 2012-03-22 | — | — | US | claimed |
| US-20090011124-A1 | Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(1-methylimidazole)2(2-ethylhexanoate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes | HSIEH BING | 2009-01-08 | — | — | US | claimed |
| EP-1778778-A2 | ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS | King Industries, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060247341-A1 | Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(tetramethylguanidine)2(formate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes | KING INDUSTRIES, INC. | 2006-11-02 | — | — | US | claimed |
| WO-2006022899-A2 | ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS | KING INDUSTRIES, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060036007-A1 | Organometallic compositions and coating compositions | KING INDUSTRIES, INC. (US) | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070569-A1 | ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS | UROD, AOC1, AOC2 | ABCC4 4397/4885MAPT 1072/4885ALDH1A1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.