Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17120959 | 0.83 | LMNA (0.32) | ALDH1A1LMNA | |
| SCHEMBL456981 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1LMNATSHR | |
| Hydrochloric Acid SCHEMBL739371 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1LMNATSHR | |
| SCHEMBL4214037 | 0.75 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL9893479 | 0.75 | PTGS1 (0.36) | GABRA1GABRB2FABP4FABP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1727636 | 0.73 | DPP4 (0.40) | GABRA1GABRB2ALDH1A1LMNATSHR | |
| SCHEMBL1076308 | 0.72 | KDM1A (0.36) | ALDH1A1LMNATSHR | |
| SCHEMBL1047507 | 0.70 | ALDH1A1 (0.39) | GABRA1GABRB2ALDH1A1LMNATSHR | |
| SCHEMBL20408268 | 0.69 | HTR7 (0.43) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL820072 | 0.69 | ALDH1A1 (0.38) | GABRA1GABRB2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316380-B1 | ONE TRANSITION METAL COMPOUND AND AT LEAST ONE N-HETEROCYCLIC CARBENE OR ITS PROTONATED SALT | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2001-11-13 | — | — | US | disclosed |