Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971768 | 0.81 | HTR2A (0.35) | TSHRHTR1DHTR1BHTR3A | |
| SCHEMBL11939021 | 0.81 | MEN1 (0.33) | LMNAHPGDHTR1DHTR1B | |
| SCHEMBL1076305 | 0.80 | HPGD (0.32) | HPGDHTR1DHTR1B | |
| SCHEMBL1076307 | 0.80 | HPGD (0.32) | HPGDHTR1DHTR1B | |
| SCHEMBL18231795 | 0.77 | — | — | |
| SCHEMBL29282855 | 0.75 | — | — | |
| SCHEMBL7873017 | 0.72 | GABRA1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL9893479 | 0.71 | PTGS1 (0.36) | LMNAALDH1A1TSHRHPGDRECQL | |
| SCHEMBL25354539 | 0.71 | KIF11 (0.42) | LMNAALDH1A1HTR1DKIF11UGT2B7 | |
| SCHEMBL456981 | 0.70 | GABRA1 (0.43) | LMNAALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639362-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-05-02 | — | — | US | disclosed |
| US-20220176362-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | Apeiron Synthesis S. A. (PL) | 2022-06-09 | — | — | US | disclosed |
| US-11291983-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2022-04-05 | — | — | US | disclosed |
| EP-3848378-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | Takasago International Corporation (JP) | 2021-07-14 | — | — | EP | disclosed |
| US-20210077988-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | Apeiron Synthesis S. A. (PL) | 2021-03-18 | — | — | US | disclosed |
| US-20170233418-A1 | N-(PHOSPHINOALKYL)-N-(THIOALKYL)AMINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METAL COMPLEX THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-08-17 | — | — | US | disclosed |
| US-9527877-B2 | Metal complexes, their application and methods of carrying out of metathesis reaction | APEIRON SYNTHESIS S.A. (PL) | 2016-12-27 | — | — | US | disclosed |
| US-9328132-B2 | Ruthenium complexes, their use in the metathesis reactions, and a process for carrying out the metathesis reaction | APEIRON SYNTHESIS S.A. (PL) | 2016-05-03 | — | — | US | disclosed |
| US-20150158896-A1 | NOVEL RUTHENIUM COMPLEXES, THEIR USE IN THE METATHESIS REACTIONS, AND A PROCESS FOR CARRYING OUT THE METATHESIS REACTION | APEIRON SYNTHESIS S.A. (PL) | 2015-06-11 | — | — | US | disclosed |
| US-20150126744-A1 | Metal Complexes, Their Application and Methods of Carrying out of Metathesis Reaction | APEIRON SUNTHESIS S.A. (PL) | 2015-05-07 | — | — | US | disclosed |
| EP-2276725-B1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | HOFFMANN LA ROCHE (CH) | 2012-07-04 | — | — | EP | disclosed |
| EP-2276725-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | F. Hoffmann-La Roche AG (CH) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009124853-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233418-A1 | N-(PHOSPHINOALKYL)-N-(THIOALKYL)AMINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METAL COMPLEX THEREOF | NSFL1C, TST, NCL | KDM1A 2443/4885LMNA 2346/4885ALDH1A1 1341/4885 |
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | ADH4, ADH5, PF4 | KDM1A 2886/4885LMNA 1455/4885ALDH1A1 219/4885 |
| US-20220176362-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | RCOR1, NFE2L2, ARL1 | KDM1A 2992/4885LMNA 1665/4885ALDH1A1 759/4885 |
| US-11639362-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | KDM1A 2886/4885LMNA 1455/4885ALDH1A1 219/4885 |
| US-20150126744-A1 | Metal Complexes, Their Application and Methods of Carrying out of Metathesis Reaction | CYC1, ABCB7, APEX1 | KDM1A 4431/4885LMNA 3152/4885ALDH1A1 905/4885 |
| US-20150158896-A1 | NOVEL RUTHENIUM COMPLEXES, THEIR USE IN THE METATHESIS REACTIONS, AND A PROCESS FOR CARRYING OUT THE METATHESIS REACTION | CYC1, REV1, POR | KDM1A 4506/4885LMNA 3802/4885ALDH1A1 872/4885 |
| US-20210077988-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | RCOR1, OXER1, ARL1 | KDM1A 3034/4885LMNA 1685/4885ALDH1A1 739/4885 |
| US-11291983-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | RCOR1, OXER1, ARL1 | KDM1A 3034/4885LMNA 1685/4885ALDH1A1 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.