Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12136422 | 0.93 | CA12 (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL31605448 | 0.91 | CA12 (0.40) | CA12CA1CA2CA4CA9 | |
| SCHEMBL1774221 | 0.91 | CA12 (0.40) | CA12CA1CA2CA4CA9 | |
| SCHEMBL2739353 | 0.91 | CA12 (0.40) | CA12CA1CA2CA4CA9 | |
| SCHEMBL287823 | 0.86 | — | — | |
| Hexadecane SCHEMBL27925858 | 0.85 | ALDH1A1 (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL28547569 | 0.85 | CA12 (0.36) | CA12CA1CA2CA4CA9 | |
| SCHEMBL2739363 | 0.83 | PTGS2 (0.36) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12857580 | 0.82 | ESR2 (0.36) | CA12CA1CA2CA4CA9 | |
| SCHEMBL1498349 | 0.81 | LMNA (0.36) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8292976-B2 | Diesel fuel additive for reducing emissions | AFTON CHEMICAL CORPORATION (US) | 2012-10-23 | — | — | US | claimed |
| US-20120066964-A1 | Additives for Reduction of Exhaust Emissions from Compression Ignition Engines | BAKER HUGHES INCORPORATED (US) | 2012-03-22 | — | — | US | claimed |
| US-20110107658-A1 | DIESEL FUEL ADDITIVE FOR REDUCING EMISSIONS | AFTON CHEMICAL CORPORATION (US) | 2011-05-12 | — | — | US | claimed |
| US-20100325944-A1 | Additives for Cetane Improvement in Middle Distillate Fuels | BAKER HUGHES INCORPORATED (US) | 2010-12-30 | — | — | US | claimed |
| WO-2008150950-A1 | ADDITIVES FOR REDUCTION OF EXHAUST EMISSIONS FROM COMPRESSION IGNITION ENGINES | BAKER HUGHES INCORPORATED (US) | 2008-12-11 | — | — | WO | claimed |
| US-20080295395-A1 | Additives for Reduction of Exhaust Emissions From Compression Ignition Engines | BAKER HUGHES INCORPORATED (US) | 2008-12-04 | — | — | US | claimed |
| CN-1718699-A | Catalytic combustion adjuvant for coal | YIN XIAOLIN (CN) | 2006-01-11 | — | — | CN | claimed |
| WO-1996025473-A1 | DIESEL FUELS | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1996-08-22 | — | — | WO | claimed |
| WO-2022096930-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-12 | — | — | WO | disclosed |
| US-9446015-B2 | Quinone based nitric oxide donating compounds for ophthalmic use | NICOX SCIENCE IRELAND (IE) | 2016-09-20 | — | — | US | disclosed |
| US-9266820-B2 | Nitric oxide donor compounds | NICOX SCIENCE IRELAND (IE) | 2016-02-23 | — | — | US | disclosed |
| US-9162969-B2 | Nitrooxyesters, their preparation and use | DSM IP ASSETS B.V. (NL) | 2015-10-20 | — | — | US | disclosed |
| US-20150283106-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NICOX SA (FR) | 2015-10-08 | — | — | US | disclosed |
| US-9079821-B2 | Quinone based nitric oxide donating compounds | NICOX SCIENCE IRELAND (IE) | 2015-07-14 | — | — | US | disclosed |
| US-4227889-A | MONOHYDROXY ALKANOL, FUEL OIL, DIMER FATTY ACID | ETHYL CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4208190-A | MONOHYDROXY ALKANOL, ALIPHATIC PRIMARY AMINE | ETHYL CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4204481-A | A MONOHYDROXY ALCOHOL AND A FATTY ACID AMIDE OR DIETHANOLAMINE | ETHYL CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4198931-A | ANTI-WEAR COMPRESSION IGNITION FUEL COMPRISING ALCOHOL AND N-HYDROXY HYDROCARBONAMIDE | ETHYL CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |
| US-4185594-A | ALKANOL, IGNITION ACCELERATOR, DIMERIZED UNSATURATED FATTY ACID | ETHYL CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| US-4177768-A | Fuel compositions | ETHYL CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283106-A1 | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE | NOS1, NOS3, NOS2 | CA12 4487/4885CA1 4736/4885CA2 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.