Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868349 | 0.91 | MAPT (0.46) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL8459364 | 0.86 | HPGD (0.44) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL7863072 | 0.86 | HPGDS (0.44) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL7863165 | 0.85 | ALOX15 (0.49) | MAPTLMNAHPGDCYP1A2CYP2C19 | |
| SCHEMBL7863171 | 0.81 | HPGD (0.43) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL7869910 | 0.78 | KCNMA1 (0.46) | MAPTLMNAMAPK1MEN1KMT2A | |
| Alcohol SCHEMBL27634214 | 0.75 | HPGD (0.56) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL7868363 | 0.74 | ALOX15 (0.54) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL11289155 | 0.74 | HPGD (0.59) | MAPTLMNAMAPK1HPGDCYP1A2 | |
| SCHEMBL7863149 | 0.74 | KCNMA1 (0.44) | MAPTLMNAMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313290-B1 | Azolobenzazepine derivatives and compositions and method of use thereof | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| US-6124281-A | TREATING STROKES | ZENECA LIMITED (GB) | 2000-09-26 | — | — | US | disclosed |