Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823749 | 0.76 | GSK3B (0.42) | GSK3BPIM1PIM2 | |
| SCHEMBL30540792 | 0.73 | RAB9A (0.42) | PIM1PIM2 | |
| SCHEMBL3668219 | 0.71 | NUDT1 (0.35) | GSK3BPIM1PIM2 | |
| SCHEMBL5562287 | 0.69 | KDM4E (0.41) | PIM1PIM2 | |
| SCHEMBL14723066 | 0.64 | PRKAG1 (0.33) | GSK3B | |
| SCHEMBL767097 | 0.63 | RXRA (0.52) | — | |
| SCHEMBL5092967 | 0.62 | POLB (0.31) | — | |
| SCHEMBL29705459 | 0.62 | GRM4 (0.38) | GSK3BPIM1PIM2 | |
| SCHEMBL19616539 | 0.62 | CHUK (0.36) | — | |
| SCHEMBL19616876 | 0.62 | PRKAB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037410-A9 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012037410-A2 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |