Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868666 | 0.74 | ADRA2C (0.46) | LMNA | |
| SCHEMBL8444492 | 0.67 | QPCTL (0.37) | LMNASMN1; SMN2 | |
| SCHEMBL9021042 | 0.63 | TAAR1 (0.41) | KMT2A | |
| Hydrochloric Acid SCHEMBL7873720 | 0.62 | TDP1 (0.41) | LMNA | |
| SCHEMBL13684790 | 0.62 | CPB2 (0.38) | KMT2A | |
| SCHEMBL17873606 | 0.62 | PTGS2 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL7877119 | 0.61 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL7873868 | 0.60 | ADRB1 (0.52) | LMNA | |
| SCHEMBL8445998 | 0.60 | QPCTL (0.48) | — | |
| SCHEMBL9097894 | 0.60 | CPB2 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |