Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889405 | 1.00 | THRB (0.36) | THRBLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5497110 | 0.67 | THRB (0.40) | THRBLMNA | |
| SCHEMBL6604249 | 0.66 | MEN1 (0.32) | — | |
| SCHEMBL7301138 | 0.64 | SLC6A2 (0.36) | THRBLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16287489 | 0.63 | SHBG (0.44) | THRBLMNA | |
| SCHEMBL2147510 | 0.63 | THRB (0.36) | THRBLMNA | |
| SCHEMBL27525521 | 0.63 | THRB (0.36) | THRBLMNA | |
| Methyl Alcohol SCHEMBL27917454 | 0.63 | THRB (0.36) | THRBLMNA | |
| SCHEMBL24806540 | 0.62 | LMNA (0.52) | THRBLMNA | |
| SCHEMBL8760918 | 0.62 | THRB (0.35) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6168934-B1 | EFFICIENT GLYCOSYLATION BY MIXING ACCEPTOR SACCHARIDE, DONOR MONOSACCHARIDE, ACTIVATING NUCLEOTIDE, ACTIVATED DONOR MONOSACCHARIDE REGENERATING SYSTEM, PYROPHOSPHATE SCAVENGER, AND GLYCOSYLTRANSFERASE IN AN AQUEOUS MEDIUM | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-02 | — | — | US | disclosed |
| EP-0576592-B1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5759823-A | MIXING IN AQUEOUS MEDIUM ACTIVATED DONOR MONOSACCHARIDE WITH ACCEPTOR SACCHARIDE IN PRESENCE OF GLYCOSYLTRANSFERASE, MAINTAINING TO GLYCOSYLATE ACCEPTOR SACCHARIDE | SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-02 | — | — | US | disclosed |
| US-5596005-A | GLYCOSIDASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-01-21 | — | — | US | disclosed |
| US-5593887-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0576592-A4 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | SCRIPPS RESEARCH INST (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5461143-A | Oligosaccharide enzyme substrates and inhibitors: methods and compositions | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0576592-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5276120-A | Reductively cyclizing an azido-substituted alpha-ketose phosphate; palladium catalyzed | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-04 | — | — | US | disclosed |
| WO-1992016640-A1 | OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-10-01 | — | — | WO | disclosed |