SCHEMBL789377

SCHEMBL789377

CC(O)c1c(O)cccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.44
GABRB2 P47870 3/20 0.44
CA2 P00918 6/20 0.43
CA1 P00915 5/20 0.43
HPGD P15428 5/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 4/20 0.43
ALOX15 P16050 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
HSD17B10 Q99714 3/20 0.43
EGFR P00533 2/20 0.43
FYN P06241 2/20 0.43
MMP9 P14780 2/20 0.43
RECQL P46063 2/20 0.43
ADAMTS4 O75173 1/20 0.43
MMP2 P08253 1/20 0.43
MMP8 P22894 1/20 0.43
CA6 P23280 1/20 0.43
CDK2 P24941 1/20 0.43
MMP12 P39900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861539 0.85 GABRA1 (0.48) GABRA1GABRB2CA2CA1HPGD
SCHEMBL29558466 0.85 TRPA1 (0.50) GABRA1GABRB2CA2CA1HPGD
SCHEMBL29558146 0.84 TSHR (0.48) GABRA1GABRB2CA2CA1HPGD
SCHEMBL29559292 0.84 TRPA1 (0.38) GABRA1GABRB2CA2CA1HPGD
SCHEMBL19971983 0.84 TSHR (0.48) GABRA1GABRB2CA2CA1HPGD
SCHEMBL17471748 0.84 CES2 (0.42) GABRA1GABRB2CA2CA1HPGD
SCHEMBL29558423 0.84 CA2 (0.38) GABRA1GABRB2CA2CA1HPGD
SCHEMBL483998 0.82 KDM4E (0.38) GABRA1GABRB2HPGDALDH1A1LMNA
SCHEMBL13239923 0.80 TP53 (0.57) CA2CA1HPGDALDH1A1LMNA
SCHEMBL725385 0.80 GABRA1 (0.52) GABRA1GABRB2CA2CA1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4237605-B1 MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER LUBRIZOL ADVANCED MAT INC (US) 2026-04-01 EP claimed
US-12515378-B2 Method of making articles from recyclable fabrics LUBRIZOL ADVANCED MATERIALS, INC. (US) 2026-01-06 US claimed
EP-4648680-A2 BIOSENSORS WITH HYDROPHILIC POLYURETHANE MEMBRANES Abbott Diabetes Care Inc. (US) 2025-11-19 EP claimed
US-12391790-B2 Articles made from hydrophilic thermoplastic polyurethane compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-08-19 US claimed
WO-2025128433-A1 MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER AND FABRIC MADE THEREFROM LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-06-19 WO claimed
EP-4237603-B1 METHOD OF MAKING ARTICLES FROM RECYCLABLE FABRICS LUBRIZOL ADVANCED MAT INC (US) 2025-02-26 EP claimed
US-20240328989-A1 BIOSENSORS WITH HYDROPHILIC POLYURETHANE MEMBRANES ABBOTT DIABETES CARE INC. (US) 2024-10-03 US claimed
WO-2024151543-A2 BIOSENSORS WITH HYDROPHILIC POLYURETHANE MEMBRANES ABBOTT DIABETES CARE INC. (US) 2024-07-18 WO claimed
US-11976159-B2 Articles made from hydrophilic thermoplastic polyurethane compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-05-07 US claimed
US-20230382015-A1 Method of Making Articles from Recyclable Fabrics LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-30 US claimed
US-20130084702-A1 ACRYLATE POLYURETHANE CHEMICAL MECHANICAL POLISHING LAYER U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2013-04-04 US claimed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US claimed
CN-100381477-C Melt spun polyether TPU fibers containing mixed polyols and process NOVEON IP HOLDINGS CORP (US) 2008-04-16 CN claimed
US-20070149752-A1 Railway freight car constant contact side bearing KENNEDY JAMES S 2007-06-28 US claimed
CN-1829754-A Melt spun polyether TPU fibers containing mixed polyols and process NOVEON IP HOLDINGS CORP (US) 2006-09-06 CN claimed
CN-1474842-A Polyester resins with improved properties �Ĵ����Ǿۺ���ع����޹�˾ 2004-02-11 CN claimed
US-5558959-A Polyurethane based electrolytes for electrochemical cells and electrochemical cells using same MOTOROLA, INC. (US) 1996-09-24 US claimed
US-4762875-A Water based printing inks for plastic and metal surfaces GOLD MARVIN H (US) 1988-08-09 US claimed
US-4762865-A Epoxy coatings for computer hard disks and metal coil decoration and protection GOLD MARVIN H (US) 1988-08-09 US claimed
US-4652388-A WATER BASED DISPERSION; ADHESIVE PLASTICIZER AND POLYMER GOLD MARVIN H (US) 1987-03-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 GABRA1 4083/4885GABRB2 3279/4885CA2 4012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.