Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891537 | 0.87 | KMT2A (0.64) | GAAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7893093 | 0.81 | PKM (0.79) | GAAMEN1KMT2APOLBPKM | |
| SCHEMBL7883722 | 0.79 | KMT2A (0.70) | GAAMEN1KMT2APOLBPKM | |
| SCHEMBL7890110 | 0.77 | LMNA (0.73) | MEN1KMT2APOLBPKMLMNA | |
| SCHEMBL5255516 | 0.76 | GAA (0.80) | GAAMEN1KMT2APOLBLMNA | |
| SCHEMBL9513007 | 0.75 | POLB (0.62) | GAAMEN1KMT2APOLBLMNA | |
| SCHEMBL7892717 | 0.74 | ALDH1A1 (0.60) | GAAMEN1KMT2APOLBLMNA | |
| SCHEMBL7890979 | 0.74 | THRB (0.74) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3714000 | 0.74 | GPR183 (0.65) | MEN1KMT2APKMLMNAL3MBTL1 | |
| SCHEMBL5915285 | 0.74 | LMNA (0.70) | MEN1KMT2APOLBPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |