SCHEMBL7895049

SCHEMBL7895049

C=CC(=O)OOC(C)C(Br)c1cccc(Br)c1Br

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607045 0.75 CYP2C9 (0.33) CYP2C9CYP2C19
SCHEMBL7896534 0.73 CYP2C9 (0.33) CYP2C9CYP2C19HTT
SCHEMBL2794002 0.72 TSHR (0.31)
Acrylic Acid Methyl Ester SCHEMBL27973734 0.69 TGM2 (0.38) CYP2C9CYP2C19HTT
SCHEMBL2884756 0.67 P2RX7 (0.41) CYP2C9CYP2C19HTT
SCHEMBL10794143 0.66 THRA (0.32) CYP2C9CYP2C19
SCHEMBL11596917 0.66 CYP2C9 (0.33) CYP2C9CYP2C19HTT
SCHEMBL1153651 0.65 CYP2C19 (0.37) CYP2C9CYP2C19HTT
SCHEMBL10627198 0.65 ALDH1A1 (0.35)
SCHEMBL5459734 0.64 TYMS (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184323-B1 FOR OPHTHALMIC LENSES ESSILOR INTERNATIONAL-COMPAGNIE GENERALE D'OPTIQUE (FR) 2001-02-06 US disclosed