Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003665 | 0.77 | BRPF1 (0.49) | ALDH1A1LMNAHTTNR4A2PARP14 | |
| SCHEMBL7890292 | 0.76 | NR4A2 (0.47) | ALDH1A1NR4A2 | |
| SCHEMBL1972827 | 0.71 | GPR84 (0.59) | ALDH1A1LMNAPKML3MBTL1 | |
| SCHEMBL29003653 | 0.71 | NR4A2 (0.46) | ALDH1A1LMNANR4A2PKML3MBTL1 | |
| SCHEMBL29003630 | 0.70 | TDO2 (0.44) | IDO1 | |
| SCHEMBL29003655 | 0.69 | RAB9A (0.49) | ALDH1A1LMNAHTTNR4A2HTR1D | |
| SCHEMBL2032138 | 0.68 | KCNQ2 (0.48) | ALDH1A1 | |
| SCHEMBL9235264 | 0.68 | GABRA1 (0.47) | NR4A2 | |
| SCHEMBL2405000 | 0.68 | MPO (0.51) | — | |
| SCHEMBL29003613 | 0.66 | HTR2B (0.59) | ALDH1A1LMNANR4A2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180657-B1 | SLEEP DISORDERS | ELI LILLY AND COMPANY | 2001-01-30 | — | — | US | disclosed |
| WO-1997000069-A1 | MELATONIN AGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA | ELI LILLY AND COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |