Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516641 | 0.81 | HTR2A (0.58) | ALDH1A1TSHRHPGDLMNAGLA | |
| SCHEMBL26693258 | 0.78 | TNF (0.76) | CSNK2A2CSNK2BCSNK2A1TNFALDH1A1 | |
| SCHEMBL26693257 | 0.78 | TNF (0.76) | CSNK2A2CSNK2BCSNK2A1TNFALDH1A1 | |
| SCHEMBL26693254 | 0.78 | TNF (0.76) | CSNK2A2CSNK2BCSNK2A1TNFALDH1A1 | |
| SCHEMBL8526104 | 0.77 | ALDH1A1 (0.47) | CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR | |
| SCHEMBL9755961 | 0.75 | ALDH1A1 (0.58) | CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR | |
| SCHEMBL5694492 | 0.75 | TDP1 (0.53) | ALDH1A1TSHRHPGDLMNAGLA | |
| SCHEMBL8528469 | 0.74 | GPR17 (0.46) | CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR | |
| SCHEMBL28751408 | 0.74 | DRD2 (0.49) | TNFALDH1A1TSHRHPGDLMNA | |
| SCHEMBL17102847 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDLMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | CANCER RESEARCH TECHNOLOGY LIMITED | 2005-09-15 | — | — | US | disclosed |
| US-6890948-B1 | Use of indole-3-acetic acid derivatives in medicine | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| EP-1296676-B1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER REC TECH LTD (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1296676-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | Cancer Research Technology Limited (GB) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002110-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | ADCY3, GPR3, HCAR3 | CSNK2A2 3683/4885CSNK2B 3786/4885CSNK2A1 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.