Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678310 | 0.84 | LOXL2 (0.55) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL28347492 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| [3-(Hydroxymethyl)Phenyl]Guanidine SCHEMBL1186272 | 0.84 | PRSS1 (0.55) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL5212905 | 0.82 | MAPT (0.46) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL8432263 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6680642 | 0.82 | LOXL2 (0.53) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL8269124 | 0.82 | SIGMAR1 (0.60) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3728364 | 0.81 | NOS1 (0.50) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL14470096 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1184796 | 0.81 | SIRT1 (0.51) | ITGB3ITGA2BSIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191273-B1 | 3,6,10,14-SUBSTITUTED-3,6,10,16-TETRAAZABICYCLO(10.3.1)-HEXADE CA-1(16),12,14-TRIENE COMPOUNDS OF GIVEN FORMULA; ANTIBACTERIAL AND OTHER UTILITIES, SUCH AS TO SCREEN FOR PESTICIDES OR DRUGS | ISIS PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | disclosed |
| WO-1999011612-A2 | SUBSTITUTED CYCLIC COMPOUNDS AND MIXTURES COMPRISING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |