Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899197 | 1.00 | DPP4 (0.43) | DPP4DPP8PARP1ANPEPFAP | |
| SCHEMBL7891694 | 0.78 | POLB (0.45) | HSD11B1 | |
| SCHEMBL7898064 | 0.72 | CHRNB2 (0.37) | — | |
| SCHEMBL7898092 | 0.71 | DRD2 (0.45) | — | |
| SCHEMBL17397452 | 0.66 | DPP4 (0.43) | DPP4DPP8PARP1ANPEPFAP | |
| SCHEMBL17397436 | 0.65 | PRCP (0.49) | DPP4DPP8PARP1ANPEPFAP | |
| SCHEMBL31494183 | 0.64 | KEAP1 (0.62) | DPP4DPP8PARP1FAP | |
| SCHEMBL26255929 | 0.64 | KEAP1 (0.62) | DPP4DPP8PARP1FAP | |
| SCHEMBL14634965 | 0.64 | ACE (0.48) | DPP4DPP8PARP1ANPEPHSD11B1 | |
| SCHEMBL14634964 | 0.64 | ACE (0.48) | DPP4DPP8PARP1ANPEPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184229-B1 | 6-pyrrolidin-2-ylpyrindine derivatives, their preparation and application in therapy | SANOFI-SYNTHELABO (FR) | 2001-02-06 | — | — | US | disclosed |