Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899940 | 0.90 | TSHR (0.47) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4745163 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7903597 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7898400 | 0.82 | HTR1A (0.44) | ALDH1A1HSD17B10SMN1; SMN2KDM4ETP53 | |
| SCHEMBL7892613 | 0.82 | PIK3CA (0.53) | ALDH1A1SMN1; SMN2KDM4EMAPTPIK3CA | |
| SCHEMBL7900211 | 0.76 | PRKCI (0.45) | ALDH1A1SMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL7892711 | 0.74 | SIGMAR1 (0.51) | ALDH1A1HSD17B10LMNAKDM4EMAPT | |
| SCHEMBL7899808 | 0.74 | TDP1 (0.42) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7901560 | 0.73 | GAA (0.52) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4745253 | 0.72 | HTT (0.53) | ALDH1A1HSD17B10SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | LOXL4, CXCR4, LTC4S | ALDH1A1 825/4885HSD17B10 2890/4885SMN1; SMN2 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.