Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786819 | 0.80 | ALDH1A1 (0.49) | TDP1KMT2AKDM4EALDH1A1MAOA | |
| SCHEMBL7898400 | 0.76 | HTR1A (0.44) | KMT2AKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7892613 | 0.76 | PIK3CA (0.53) | TDP1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL7899744 | 0.74 | ALDH1A1 (0.44) | KMT2AKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL7900197 | 0.72 | SYK (0.40) | KMT2AKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7899961 | 0.72 | GABRP (0.38) | KMT2AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL7898100 | 0.67 | FOS (0.36) | KMT2ATP53MEN1TSHRMAPT | |
| SCHEMBL4787080 | 0.66 | LMNA (0.50) | TDP1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL7899726 | 0.65 | RELA (0.52) | MAPT | |
| SCHEMBL285074 | 0.64 | CYP11B1 (0.73) | KMT2AALDH1A1MAOAMAOBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | LOXL4, CXCR4, LTC4S | TDP1 443/4885KMT2A 4045/4885KDM4E 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.