Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CES1 | P23141 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752481 | 1.00 | PPIA (0.79) | PPIALMNAGAAMAPK1CES1 | |
| SCHEMBL790294 | 0.91 | GAA (0.86) | LMNAGAAMAPK1PGRALDH1A1 | |
| SCHEMBL29561510 | 0.89 | PGR (0.72) | PPIALMNAGAAMAPK1CES1 | |
| SCHEMBL27180069 | 0.87 | PPIA (0.73) | PPIALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27181616 | 0.87 | PPIA (0.73) | PPIALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL32679643 | 0.86 | GAA (0.78) | LMNAGAAMAPK1PGRALDH1A1 | |
| SCHEMBL6554630 | 0.86 | CES1 (1.00) | GAACES1PGRALDH1A1CYP19A1 | |
| SCHEMBL2474197 | 0.86 | CES1 (1.00) | GAACES1PGRALDH1A1CYP19A1 | |
| SCHEMBL7531903 | 0.85 | PGR (0.62) | PPIALMNAGAAMAPK1CES1 | |
| SCHEMBL30434229 | 0.85 | GAA (0.76) | LMNAGAAMAPK1PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130331456-A1 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. | 2013-12-12 | — | — | US | disclosed |
| EP-2616073-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | Microbiotix, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| US-6706748-B2 | USE AS MICROBICIDES | NIHON BAYER AGROCHEM, K.K. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030220197-A1 | Isothiazole derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-1284970-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130331456-A1 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | HAVCR2, PIGS, ZC3HAV1 | PPIA 616/4885LMNA 3491/4885GAA 1278/4885 |
| US-20030220197-A1 | Isothiazole derivatives | IRF3, MSR1, ARG1 | PPIA 3341/4885LMNA 4878/4885GAA 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.