Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900093 | 0.92 | BTK (0.44) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL7899044 | 0.73 | TRPV3 (0.38) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL7901506 | 0.73 | GPR119 (0.42) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL2792636 | 0.72 | CCNK (0.44) | USP30MEN1KMT2ATRPV3HPGDS | |
| SCHEMBL7900422 | 0.71 | BTK (0.44) | USP30BTKMEN1KMT2AHPGDS | |
| SCHEMBL7898726 | 0.69 | USP30 (0.46) | USP30MEN1KMT2ACNR1CNR2 | |
| SCHEMBL2791157 | 0.69 | TRPV3 (0.43) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL7898292 | 0.69 | BTK (0.42) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL7900912 | 0.69 | TRPV3 (0.40) | USP30BTKMEN1KMT2ATRPV3 | |
| SCHEMBL28297852 | 0.68 | TRPV3 (0.52) | USP30TRPV3HPGDSGPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |