SCHEMBL8053167

SCHEMBL8053167

Cc1cccc(C2=C3C(=O)N(C(=O)OC(C)(C)C)C(c4cccc(C)c4)=C3C(=O)N2C(=O)OC(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.42
BCHE P06276 1/20 0.40
RIPK2 O43353 1/20 0.36
DPP4 P27487 1/20 0.36
KAT6A Q92794 1/20 0.36
KAT5 Q92993 1/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.35
USP30 Q70CQ3 1/20 0.35
GRM5 P41594 1/20 0.35
HSD17B10 Q99714 1/20 0.34
NR1H2 P55055 3/20 0.34
CRBN Q96SW2 1/20 0.34
PTPN5 P54829 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754292 0.92 CNR1 (0.39) GPR119BCHEKAT6AKAT5LMNA
SCHEMBL8069949 0.85 XPO1 (0.43) BCHEUSP30GRM5
SCHEMBL902929 0.84 BCHE (0.48) GPR119BCHEALDH1A1USP30HSD17B10
SCHEMBL8949810 0.83 GPR119 (0.40) GPR119BCHELMNAALDH1A1HSD17B10
SCHEMBL7755310 0.77 KMT2A (0.40) GPR119BCHELMNAHSD17B10MAPT
SCHEMBL12393913 0.77 GPR119 (0.44) GPR119BCHEALDH1A1GRM5
SCHEMBL7900611 0.77 BCHE (0.42) GPR119BCHEUSP30MAPTNPSR1
SCHEMBL24565414 0.77 BCHE (0.40) GPR119BCHELMNAALDH1A1NR1H2
SCHEMBL12393911 0.76 GPR119 (0.41) GPR119BCHEUSP30
SCHEMBL6322676 0.76 MEN1 (0.43) BCHEMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654506-B1 Process for the manufacture of synergetic mixtures of pigments CIBA SC HOLDING AG (CH) 2000-05-17 EP disclosed
US-5518539-A COLORFASTNESS FOR ORGANIC PIGMENT MIXTURES FOR SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-05-21 US disclosed
EP-0654506-A2 Process for the manufacture of synergetic mixtures of pigments CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed