Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901144 | 0.84 | KMT2A (0.62) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2068236 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30737452 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30737455 | 0.81 | PGR (0.52) | PTGES2POLBKMT2A | |
| SCHEMBL30737349 | 0.81 | PGR (0.62) | PTGES2ATM | |
| Hydrochloric Acid SCHEMBL29885455 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL14160374 | 0.78 | MCL1 (0.51) | PTGES2POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13618096 | 0.78 | HTR6 (0.48) | PTGES2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL15690985 | 0.77 | KEAP1 (0.66) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5595350 | 0.77 | DDX3X (0.71) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022207-A1 | BIS-SULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-02-24 | — | — | WO | disclosed |