SCHEMBL30737455

SCHEMBL30737455

Nc1ccccc1NS(=O)(=O)c1cccc(F)c1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.52
PTGES2 Q9H7Z7 3/20 0.51
GBA1 P04062 1/20 0.51
SLC10A2 Q12908 1/20 0.51
SLC10A1 Q14973 1/20 0.51
SLC10A6 Q3KNW5 1/20 0.51
KMT2A Q03164 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
POLB P06746 1/20 0.46
AURKA O14965 1/20 0.46
KDR P35968 1/20 0.46
AURKB Q96GD4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561655 0.82 MEN1 (0.66) KMT2A
SCHEMBL30737629 0.82 MEN1 (0.66) KMT2A
SCHEMBL30737452 0.81 ALDH1A1 (0.58) KMT2AFFAR4
SCHEMBL2068236 0.81 ALDH1A1 (0.58) KMT2AFFAR4
SCHEMBL7901144 0.81 KMT2A (0.62) SLC10A2SLC10A1SLC10A6KMT2APOLB
SCHEMBL30737349 0.81 PGR (0.62) PGRPTGES2
SCHEMBL1260477 0.81 PTGES2 (0.47) PTGES2KMT2APOLB
Hydrochloric Acid SCHEMBL29885455 0.80 ALDH1A1 (0.56) KMT2AFFAR4
SCHEMBL23529984 0.79 LMNA (0.48) PGRGBA1SLC10A2SLC10A1SLC10A6
SCHEMBL13618096 0.78 HTR6 (0.48) PTGES2KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510460-A Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof 贵州大学 2024-02-06 CN disclosed