Toluene

Toluene

SCHEMBL7901170

Cc1ccccc1.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
TSHR P16473 2/20 0.55
ALOX12 P18054 1/20 0.55
ACHE P22303 1/20 0.55
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 1/20 0.50
TP53 P04637 1/20 0.50
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
MAPT P10636 2/20 0.41
AKR1C3 P42330 1/20 0.41
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL28016180 0.85 ALDH1A1 (0.50) TSHRACHEALDH1A1CYP1A2TP53
Toluene SCHEMBL11041731 0.84 LMNA (0.39) LMNATSHRALOX12ACHEALDH1A1
Pivalate SCHEMBL27449045 0.82 LMNA (0.58) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL124611 0.81 LMNA (0.65) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL1850918 0.81 LMNA (0.65) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL4861938 0.81 LMNA (0.65) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL7355317 0.81 LMNA (0.73) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL48134 0.81 LMNA (0.73) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL4498352 0.81 TSHR (0.73) LMNATSHRALOX12ACHEALDH1A1
Toluene SCHEMBL2914390 0.81 LMNA (0.73) LMNATSHRALOX12ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599664-B Glycoside compound, amide compound, and method for producing polynucleotide using these compounds 住友化学株式会社 2025-03-28 CN disclosed
CN-114502566-B Method for producing nucleic acid oligomer 住友化学株式会社 2025-02-11 CN disclosed
CN-115003680-B Method for preparing nucleic acid oligomer 住友化学株式会社 2025-01-28 CN disclosed
CN-113646083-B Inorganic porous carrier and method for producing nucleic acid using same 住友化学株式会社 2024-06-07 CN disclosed
CN-113677432-B Inorganic porous carrier and method for producing nucleic acid using same 住友化学株式会社 2024-06-07 CN disclosed
CN-111684073-B Method for producing nucleic acid molecule 住友化学株式会社 2024-01-05 CN disclosed
CN-115551805-B Inorganic porous substrate, inorganic porous support, and method for producing nucleic acid 住友化学株式会社 2023-10-20 CN disclosed
CN-112020507-B Amide compound and method for producing polynucleotide using same 住友化学株式会社 2023-10-10 CN disclosed
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-17 US disclosed
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-03 US disclosed
CN-106749928-A The composition and preparation method of a kind of GMA graft modifications LLDPE 黄山贝诺科技有限公司 2017-05-31 CN disclosed
US-20150315229-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-11-05 US disclosed
EP-2921499-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID Takeda Pharmaceutical Company Limited (JP) 2015-09-23 EP disclosed
US-6326494-B1 LASER DYES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6184378-B1 PIGMENTS, LASER DYES AND PRECURSORS FOR PREPARING FLUORESCENT DYES, POLYMERIC COLORANTS, BASF AKTIENGESELLSCHAFT (DE) 2001-02-06 US disclosed
US-6143905-A REACTING 1,7-DIBROMOPERYLENE-3,4,9,10-TETRACARBOXYLIC DIANHYDRIDE OR TETRACARBOXYLIC ACID IN PRESENCE OF APROTIC SOLVENT WITH A PRIMARY AMINE TO FORM DIIMIDE, REACTING DIIMIDE WITH AROMATIC ALOCHOL OR THIOL, AND HYDROLYZING BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
US-6136976-A REACTING PERYLENE-3,4,9,10-TETRACARBOXYLIC ACID OR ITS ANHYDRIDE WITH AN AMIDE IN PRESENCE OF INTER DILUENT AND TRANSITION METAL CATALYST OR ZINC METAL OR SALT CATALYST UNDER SUPERATMOSPHERIC PRESSURE BASF AKTIENGESELLSCHAFT (DE) 2000-10-24 US disclosed
US-6063181-A 1,7-disubstituted perylene-3,4,9, 10-tetracarboxylic acids, their dianhydrides and diimides of said acids BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
US-5808073-A CATALYTIC AMINATION OF THE CORRESPONDING PERYLENETETRACARBOXYLIC ACID OR ANHYDRIDE WITH PRIMARY AMINE IN TERTIARY AMINE SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
US-4508912-A UNING METAL OXIDE, HYDROXIDE, ACID OR ACID SALT, OR ORGANOBASIC COMPOUND CATALYST AJINOMOTO COMPANY, INCORPORATED (JP) 1985-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150315229-A1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID POLM, POLRMT, RNMT LMNA 233/4885TSHR 495/4885ALOX12 2904/4885
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD DNMT3L, FBL, SIK1 LMNA 373/4885TSHR 4846/4885ALOX12 3594/4885
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER FBL, POLI, POLL LMNA 1361/4885TSHR 1662/4885ALOX12 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.