SCHEMBL7902242

SCHEMBL7902242

CCCPc1ccccc1PCCC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7558656 0.85 ACHE (0.39)
SCHEMBL6682709 0.84 GABRA1 (0.38) TP53
SCHEMBL5390055 0.80 ALDH1A1 (0.40)
SCHEMBL7765785 0.80 CA1 (0.46) TP53
SCHEMBL28241024 0.80 PNMT (0.39)
SCHEMBL28240930 0.79 LIPG (0.42)
SCHEMBL28226718 0.77 TRPA1 (0.37) TP53
SCHEMBL30616086 0.77 TP53 (0.36) TP53
SCHEMBL22288227 0.76 ALDH1A1 (0.36) SIGMAR1
SCHEMBL940829 0.76 TP53 (0.38) TP53SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194593-B1 USEFUL AS LIGAND FOR AN ASYMMETRIC CATALYST FOR USE IN ASYMMETRICAL HYDROGENATION NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2001-02-27 US disclosed