Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 14/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933966 | 0.91 | ITGB1 (0.37) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL6931396 | 0.91 | SLC7A5 (0.34) | ITGA4ITGB1ITGB3ITGB7PTPN1 | |
| SCHEMBL7908666 | 0.85 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL6931447 | 0.84 | CTSL (0.40) | PTPN1PRSS1TMPRSS15 | |
| SCHEMBL8200203 | 0.84 | TPH1 (0.38) | PTPN1TPH1 | |
| SCHEMBL7908715 | 0.82 | FNTA (0.33) | — | |
| SCHEMBL7896744 | 0.81 | FNTA (0.34) | — | |
| SCHEMBL6933976 | 0.79 | ITGA4 (0.46) | ITGA4ITGB1 | |
| SCHEMBL6932583 | 0.79 | PTPN1 (0.46) | ITGB3PTPN1ITGA2BTPH1 | |
| SCHEMBL6934284 | 0.79 | ITGA4 (0.38) | ITGA4ITGB1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |