Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915334 | 0.85 | DHFR (0.32) | — | |
| SCHEMBL7902988 | 0.85 | GRIN1 (0.32) | CNR1CNR2 | |
| SCHEMBL7902852 | 0.85 | NPC1 (0.34) | CNR2 | |
| SCHEMBL7914652 | 0.83 | DYRK3 (0.37) | — | |
| SCHEMBL7912990 | 0.82 | PARP1 (0.37) | PIM1 | |
| SCHEMBL7913253 | 0.80 | MAOB (0.34) | — | |
| SCHEMBL7913078 | 0.80 | DYRK3 (0.37) | — | |
| SCHEMBL7916997 | 0.80 | JAK2 (0.35) | — | |
| SCHEMBL7929296 | 0.80 | DYRK3 (0.49) | PIM1 | |
| SCHEMBL7911686 | 0.78 | PGR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |