Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904632 | 0.87 | HRH3 (0.41) | CYP2D6TSHRALDH1A1MEN1CYP1A2 | |
| SCHEMBL7904007 | 0.87 | USP2 (0.40) | ALDH1A1MEN1KMT2AHRH3KDM4E | |
| SCHEMBL7904674 | 0.84 | QPCT (0.51) | CYP2D6TSHRHRH3ATMKDM4E | |
| SCHEMBL7905773 | 0.81 | BACE1 (0.39) | CYP2D6ALDH1A1CYP1A2HRH3KDM4E | |
| SCHEMBL7896424 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHRH3KCNH2 | |
| SCHEMBL7908545 | 0.78 | PRKDC (0.39) | CYP2D6CYP1A2KDM4ETDP1POLB | |
| SCHEMBL7896551 | 0.76 | CNR2 (0.36) | TSHRMEN1KMT2AHRH3KDM4E | |
| SCHEMBL7905780 | 0.75 | HRH3 (0.40) | TSHRALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL7896411 | 0.75 | USP2 (0.43) | CYP2D6TSHRALDH1A1CYP1A2HRH3 | |
| SCHEMBL7908481 | 0.75 | PIK3CB (0.44) | TSHRMEN1KMT2AHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |