Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903918 | 0.96 | ATM (0.34) | HTR7ALDH1A1KDM4EADRB2ADRB1 | |
| SCHEMBL7908482 | 0.91 | ALDH1A1 (0.32) | ALDH1A1KDM4EHTR1BATM | |
| SCHEMBL7902642 | 0.85 | HTR1B (0.36) | HTR7ALDH1A1KDM4EADRB2ADRB1 | |
| SCHEMBL7896515 | 0.83 | HTR1B (0.38) | HTR7ALDH1A1KDM4EADRB2ADRB1 | |
| SCHEMBL7905806 | 0.81 | HTR7 (0.40) | HTR7ALDH1A1KDM4ESMN1; SMN2NOS3 | |
| SCHEMBL7904733 | 0.80 | RAB9A (0.40) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7904672 | 0.80 | HTR1B (0.39) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7903818 | 0.79 | ATM (0.34) | HTR7ALDH1A1KDM4ENOS3NOS1 | |
| SCHEMBL7905809 | 0.78 | KDM4E (0.36) | ALDH1A1KDM4E | |
| SCHEMBL7905274 | 0.78 | HRH3 (0.41) | HTR7ALDH1A1KDM4ESMN1; SMN2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |