Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351993 | 0.89 | — | — | |
| SCHEMBL15255350 | 0.88 | ALDH1A1 (0.41) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL13668902 | 0.87 | SMO (0.34) | ALDH1A1KDM4EKMT2AMEN1SMO | |
| SCHEMBL12015831 | 0.82 | PAOX (0.39) | LMNACA1CA2CA9SMO | |
| SCHEMBL7910011 | 0.80 | DRD2 (0.45) | KMT2AMEN1PKMPOLBSMO | |
| SCHEMBL16190266 | 0.80 | POLB (0.35) | ALDH1A1KDM4EKMT2APKMPOLB | |
| SCHEMBL2229127 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL9790 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2417 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL12015832 | 0.79 | CARM1 (0.41) | ALDH1A1CHRM2CHRM1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230246229-A1 | ORGANIC SULFONATE ELECTROLYTE ADDITIVES FOR ZINC BATTERIES | Octet Scientific, Inc. | 2023-08-03 | — | — | US | disclosed |
| US-20170009275-A1 | SUBSTRATES AND METHODS USEFUL IN SEQUENCING | Life Technologies Corporation | 2017-01-12 | — | — | US | disclosed |
| US-9527824-B2 | Pharmaceutical composition for preventing or treating cognitive impairment-related disease comprising morpholine or piperazine based compounds, and donepezil | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-12-27 | — | — | US | disclosed |
| US-9220760-B2 | Method of modulating the proliferation of medullary thyroid carcinoma cells | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150299787-A1 | IMMOBILIZED BUFFER PARTICLES AND USES THEREOF | Life Technologies Corporation | 2015-10-22 | — | — | US | disclosed |
| US-20150005306-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING COGNITIVE IMPAIRMENT-RELATED DISEASE COMPRISING MORPHOLINE OR PIPERAZINE BASED COMPOUNDS, AND DONEPEZIL | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-01-01 | — | — | US | disclosed |
| US-20110318820-A1 | Immobilized Buffer Particles and Uses Thereof | Life Technologies Corporation (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110183416-A1 | Method of modulating the proliferation of medullary thyroid carcinoma cells | IPSEN PHARMA S.A.S. (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20100261706-A1 | SUBSTITUTED TETRACYCLIC 1H-INDENO [1,2-B]PYRIDINE-2(5H)-ONE ANALOGS THEREOF AND USES THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100261706-A1 | SUBSTITUTED TETRACYCLIC 1H-INDENO [1,2-B]PYRIDINE-2(5H)-ONE ANALOGS THEREOF AND USES THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-10-14 | — | — | US | disclosed |
| WO-2010077663-A2 | SUBSTITUTED TETRACYCLIC 1H-INDENO (1,2-B) PYRIDINE-2 (5H)-ONE ANALOGS THEREOF AND USES THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20070259811-A1 | Method of modulating the proliferation of medullary thyroid carcinoma cells | IPSEN PHARMA S.A.S. (FR) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183416-A1 | Method of modulating the proliferation of medullary thyroid carcinoma cells | TRHR, THRB, TSHR | ALDH1A1 4723/4885KDM4E 4208/4885CHRM2 2107/4885 |
| US-20100261706-A1 | SUBSTITUTED TETRACYCLIC 1H-INDENO [1,2-B]PYRIDINE-2(5H)-ONE ANALOGS THEREOF AND USES THEREOF | TNNI3, TNNT2, ALDH1A2 | ALDH1A1 46/4885KDM4E 3177/4885CHRM2 1373/4885 |
| US-20070259811-A1 | Method of modulating the proliferation of medullary thyroid carcinoma cells | SSTR2, SSTR1, SSTR4 | ALDH1A1 4053/4885KDM4E 4003/4885CHRM2 1929/4885 |
| US-20150005306-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING COGNITIVE IMPAIRMENT-RELATED DISEASE COMPRISING MORPHOLINE OR PIPERAZINE BASED COMPOUNDS, AND DONEPEZIL | PSEN1, PSEN2, APP | ALDH1A1 2833/4885KDM4E 2182/4885CHRM2 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.