Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 4/20 | 0.35 |
| ▸ | TYR | P14679 | 5/20 | 0.34 |
| ▸ | GRB2 | P62993 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL7906184 | 0.87 | SLC7A5 (0.52) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7904116 | 0.85 | SLC7A5 (0.45) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7906150 | 0.83 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7906161 | 0.83 | GRB2 (0.47) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL6932583 | 0.82 | PTPN1 (0.46) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7904119 | 0.81 | CYP3A4 (0.38) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7906163 | 0.80 | L3MBTL1 (0.36) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL6935180 | 0.80 | DPP4 (0.47) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL6931447 | 0.79 | CTSL (0.40) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL6934218 | 0.79 | PTPN1 (0.43) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |