Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | FAP | Q12884 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | TPH1 | P17752 | 4/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL7906184 | 0.87 | SLC7A5 (0.52) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL6934218 | 0.85 | PTPN1 (0.43) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL7904116 | 0.85 | SLC7A5 (0.45) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL6932583 | 0.84 | PTPN1 (0.46) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL7902867 | 0.83 | SLC7A5 (0.39) | GRB2TPH1SLC7A5ALPIPKM | |
| SCHEMBL7906150 | 0.83 | SLC7A5 (0.43) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL7906163 | 0.82 | L3MBTL1 (0.36) | GRB2SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL6933972 | 0.81 | MAOB (0.46) | PTPN1DPP4FAPDPP8DPP9 | |
| SCHEMBL7904114 | 0.81 | CYP3A4 (0.37) | GRB2PTPN1TPH1SLC7A5ALPI | |
| SCHEMBL7906194 | 0.81 | ITGA4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |