Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542621 | 0.84 | F10 (0.53) | F10PTGS2 | |
| SCHEMBL21753376 | 0.84 | F10 (0.53) | F10PTGS2 | |
| SCHEMBL3864241 | 0.84 | F10 (0.60) | F10PTGS2 | |
| SCHEMBL21753351 | 0.84 | F10 (0.53) | F10PTGS2 | |
| SCHEMBL7895104 | 0.82 | MAP4K1 (0.53) | F10PTGS2 | |
| SCHEMBL92872 | 0.81 | PTGS2 (0.64) | F10PTGS2 | |
| SCHEMBL76302 | 0.80 | F10 (0.50) | F10PTGS2 | |
| SCHEMBL85537 | 0.80 | LIPE (0.52) | F10 | |
| SCHEMBL76558 | 0.80 | F10 (0.58) | F10PTGS2 | |
| SCHEMBL1679537 | 0.79 | F10 (0.52) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-10 | — | — | US | disclosed |
| WO-2017155991-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-09-14 | — | — | WO | disclosed |
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | SQOR, MAVS, TFAM | F10 3824/4885PTGS2 307/4885ALDH1A1 1628/4885 |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | F10 2854/4885PTGS2 3349/4885ALDH1A1 1182/4885 |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | SQOR, MAVS, TFAM | F10 3824/4885PTGS2 307/4885ALDH1A1 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.