Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783785 | 0.80 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| SCHEMBL29640466 | 0.80 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| SCHEMBL12745709 | 0.80 | DGAT1 (0.53) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| SCHEMBL13853899 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL7292271 | 0.79 | DGAT1 (0.51) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| Ethyl Nicotinate SCHEMBL24853 | 0.79 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| Ethyl Nicotinate SCHEMBL29958752 | 0.79 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.79 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| Ethyl Nicotinate SCHEMBL1330922 | 0.79 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| Hydrochloric Acid SCHEMBL1461215 | 0.79 | DGAT1 (0.51) | L3MBTL1ALDH1A1MAPTTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046581-A1 | Factor XIa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-02-18 | — | — | US | disclosed |
| US-6207676-B1 | Bicyclic amines | ZENECA LIMITED (GB) | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046581-A1 | Factor XIa Inhibitors | F11, F12, TFPI | L3MBTL1 4518/4885ALDH1A1 2920/4885MAPT 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.